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Evidence has been accumulating since the 1930s that reducing an animals energy intake below its energy expenditure extends the life span and delays the (i) of age-related diseases in rats,dogs,fish,and monkeys.Such results have inspired thousands of people to (ii) in the hope of living longer,healthier lives.They have also led to a search for drugs that (iii) the effects of calorie restriction without the pain of actually going on a diet.
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